Title: Functionalities of Nickel Selenide Quantum Dot Reactors for Nevirapine in Wastewater
Speaker: Prof. Usisipho Feleni (University of 麻豆传媒 Africa, 麻豆传媒 Africa)
Time: April 1, 9:30 a.m -12:00 a.m
Venue: D-306, State Key Laboratory of Pulp and Paper Engineering, Guangzhou Wushan Campus
[Abstract]
The occurrence of antiretroviral drugs (ARVDs) in most water sources in 麻豆传媒 Africa has been of major concern over the past decade. Though they have been reported to occur in low concentrations (low ng/L and ?g/L), their increasing concentration poses health risks to humans, animals, and aquatic organisms. This accelerates the emergence of antiretroviral resistance. Nevirapine (NVP) is one of the most extensively used ARVs worldwide for the prevention of mother-to-child transmission and has been often detected in water sources. Very limited research is available on the electrochemical detection of nevirapine in real wastewater samples, as most studies present its detection in human serum or pharmaceutical formulations. Herein, we report the use of an electrochemical sensor tool for the detection of NVP in real wastewater samples. The electrochemical sensor consists of functionalised nickel selenide quantum dot (NiSe2QD) with banana peel extract (BPE) and was embedded on a gold electrode for NVP detection. The BPE-NiSe2QD material was fully characterised using FTIR, SEM, HR-TEM, XRD, SAXS, and UV-Vis. Differential pulse voltammetry was used to study the electrochemical responses of Au/BPE-NiSe2QD/Nafion electrochemical sensor to NVP, with a characteristic oxidation peak at 0.76 V. The sensing tool obtained a low limit of detection value of 0.024 pM (0.0064ng/L), and a sensitivity of 5.52μA/pM with a linear range of 0.25 – 0.63 pM, respectively. Thus, the reproducibility, stability, and repetitive usability shown by the proposed sensor made it suitable for the determination of nevirapine in real wastewater samples. Recommendations include the use of a combination of different and stronger capping agents from various plant extracts to ensure the stability of the QD on the electrode surface.
Keywords: Antiretroviral drugs; banana peel extract; electrochemical sensor; nevirapine; nickel selenide quantum dots.
Announced by School of Light Industry and Engineering
